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The following message was posted to: PharmPK
Although the documentation is poor, Kovarik et al (1993) did not
demostrated a pharmacokinetic interaction when a single dose of
cyclosporine was given to healthy volunteers (adults) with steady-
state aspirin concentrations. The pharmacokinetic parameters of
cyclosporine did not differ statistically when aspirin was
coadministered.
Perhaps your female patient is a special case.
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)