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The following message was posted to: PharmPK
Dear MEMBERS in the PharmPK group:
I would appreciate any comments on the phenomenon I am observing: What would
be an explanation for a similar Cmax irrespective of the increasing doses
following intranasal administrations of a drug? I am sure there is a
saturation issue here, can I address the saturation issues by Cmax? What
would be the best approach to interpreting this kind of issue? Is
deconvolution applicable to this kind of result? (I, myself, do not think
that it is appropriate).
I am looking forward to your response(s).
Yan-Ling He, Ph.D, D.Phil.
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