PharmPK Discussion - Small intestine weight

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On 11 Sep 2001 at 10:38:17, "Kajbaf, Mahmud" (mk30297.at.GlaxoWellcome.co.uk) sent the message


I've been using small intestinal S9 from rat, dog, human and Cynomolgus
monkey. My aim is to calculate internsic and intestinal clearances of NCEs
in  rat, dog, human and Cynomolgus monkey. I need to know mg protein/g small
intestine  and small intestine  weight in all these species.I also would
like to have information about Cynomolgus monkey body and liver weight. Does
anyone have any suggetions as to where to obtain physiological parameters
that I can use in my calculations with confidance?
Thank you

Mahmud Kajbaf, PhD
GlaxoSmithKline S.p.A
CEDD DMPK.
Applied Technologies.
Via Fleming, 4
37100 Verona
Italy
Tel:+39 045-9219104
Fax: +39 045-9218153
E-mail: Mk30297.aaa.glaxowellcome.co.uk

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