PharmPK Discussion - 17AA and "First Pass" metabolism

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On 10 Dec 2002 at 18:29:31, JGUNS (JGUNS.at.ziplip.com) sent the message


The following message was posted to: PharmPK

Can someone help to shed light as to whether the Oral Anabolic Steroid
Stanazolol (17 Alpha Alkylated)  would be considered less "harsh" on
the liver when injected as opposed to oral delivery due to the fact
that it avoids the "first Pass" metabolism?  If it is less harsh, why
is that so?  I cannot find any relevant studies on this topic..

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