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Hi PharmPK members,
Can any one tell whether Azamulin (known to be a selective CYP 3A4
inhibitor) has any cross selectivity to P-gp which is a common
observation with CYP 3A4 inhibitors.
Thanks,
Kasiram.
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Kasiram,
I have not come across a comprehensive analysis/papers of the potential
of
Azamulin to have any cross selectivity to Pgp.
Gentest had presented a poster on Azamulin and CYP3A4, you might want to
give them a call to see if they know if it interacts with Pgp.
Gentest 800.343.2035
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)