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The following message was posted to: PharmPK
I remember there are a couple of wonderful papers from the group of
Chiou WL in the University of Illinois, studying the role of
erythrocytes as a total barrier for renal excretion and hepatic
elimination. There is also one short chapter on the B/P ratios in the
"Clinical Pharmacokinetics" by Rowland and Tozer (in the appendix).
I hope this helps.
Yan-Ling HE, Ph.D.
Department of Anesthesia
MGH, Harvard Medical School
55 Fruit Street
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