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Dear all
Concerning BA/BE studies, when and why is it possible the use of the
BQL/2 for BQL values. Is there any bibliographic reference ?
Thank you very much
Nuno Silva
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Two excellent papers in J. Pharmacokin. Pharmacodyn., 28(5), Oct. 2001:
J.P. Hing, S.G. Wolfrey, D. Greenslade, P.M.C. Wright: Analysis of
toxicokinetic data using NONMEM: impact of quantification limit and
replacement strategies for censored data, pp. 465-479.
S. Beal: Ways to fit a pharmacokinetic model with some data below the
quantification limit, pp. 481-504.
Laszlo Endrenyi
University of Toronto
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