PharmPK Discussion - Creatinine excretion in children

PharmPK Discussion List Archive Index page

On 15 Mar 2002 at 11:04:48, "Michael C. Kohn" (kohn.aaa.valiant.niehs.nih.gov) sent the message


The following message was posted to: PharmPK

Does anyone know how much creatinine is excreted in urine by children
(mg/kg/day)? I've seen values in the literature of about 10-15 mg/kg/day
(but no real data). The most recent measurement I could find is 11.3
mg/kg/day. This is somewhat lower than found for adults (even women).

Michael C. Kohn

Laboratory of Computational Biology and Risk Analysis National Institute
of Environmental Health Sciences P.O. Box 12233, Mail Drop A3-06
Research Triangle Park, NC 27709-2233

E-mail: kohn.at.niehs.nih.gov (Work)
Web site: http://dir.niehs.nih.gov/dirlcbra/kohn

Back to the Top

On 18 Mar 2002 at 10:21:18, =?iso-8859-1?Q?Fr=E9d=E9ric?= BOIS (Frederic.Bois.-a-.ineris.fr) sent the message


Hi Michael!

Some people here measured creat excretion recently in 21 kids of age 2 to 3 y.
They had 183 samples. Mean creatinine (in g/L) in urine was 0.49 (SD: 0.3),
median: 0.43, min 0.05, max 2.31. For their parents the values were
1.24 (+- 0.59)
1.2; 0.2; 2.74 respect. I don't have the weight or the urine
excretion rate but you
could work with reasonable assumptions.

Frederic Bois

Frederic Y. Bois,
Unite de Toxicologie Experimentale, responsable
INERIS
Parc ALATA, PB2
60550 Verneuil en Halatte
FRANCE
email: frederic.bois.-at-.ineris.fr
web: http://www.ineris.fr

Back to the Top

Want to post a follow-up message on this topic? If this link does not work with your browser send a follow-up message to PharmPK@boomer.org with "Creatinine excretion in children" as the subject

PharmPK Discussion List Archive Index page