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Does anyone have information about the effects of milk on pharmacokinetics
(Cmax, tmax) of drug ?
Thanks in advance.
Best Regards,
Seong Ryul Kim
Otsuka Pharmaceutical Co., Ltd.
e-mail:kims.-at-.clin.otsuka.co.jp
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Kim,
This article may be helpful.
Greenberger PA, Odeh YK, Frederiksen MC, Atkinson AJ Jr.
Pharmacokinetics of prednisolone transfer to breast milk.
Clin Pharmacol Ther. 1993 Mar;53(3):324-8.
PMID: 8453851 [PubMed - indexed for MEDLINE]
Zhao Wang
Otuska Maryland Research Institute
CMMP
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Dear Kim,
This may also be helpful:
"Zent C, Smith P. Study of the effect of concomitant food on the
bioavailability of rifampicin, isoniazid and pyrazinamide. Tubercle and
Lung Disease 1995; 76(2): 109-113."
Kind regards,
Jennifer Norman
Division of Pharmacology
University of Cape Town
PharmPK Discussion List Archive Index page
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