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A quick question for the group!
Are there any references (or personal experience) for
the maximal IV infusion rate during the certain
duration period in the experimental animals (such as
dog, rat etc), regardless of the toxicity of the
Some compounds we worked with have the solubility
issue. In order to test the pharmacological effects in
the desired species, we might need to use the maximal
possible infusion rate which still can maintain
animal's physiological situation.
Any input will be highly appreciate! You can directly
email to me. Thanks ahead!
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