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The following message was posted to: PharmPK
Does anyone here know what the average elimination half life of
octreotide in dogs is?
Glenn
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The following message was posted to: PharmPK
Based on Radio-activity measurements half life of Octrotide is 57 and
126 min. The half-life of unlabeled octrotide is 90-120 minutes. However
half life tend to be longer during the continuous treatment with
somatostatin analogs.
Ref: Marbach PU et. al " From Somatostatin to sandostatin:
Pharmacokinetics and Pharmacodynamics. Metabolism 41(Suppl. 2): 7-10,
1992.
Hope this helps.
Prasad Tata
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