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Hi, I am in the process of developing a post-graduate course in
Biopharmaceutics focussing on physico-chemical principles underlying
formulation and drug delivery systems. To facilitate this development, I
wandered if anyone had available any material in this area which could
be made available on-line? Topics to be covered include:
Solubility and methods of enhancing solubility
Mechanisms of drug absorption
Routes of drug administration
Controlled release delivery systems
Novel approaches to drug delivery
I would very much appreciate if you could post this on your PK listserv.
School of Pharmacy,
Steele Building (St Lucia),
The University of Queensland,
Brisbane, QLD 4072, Australia
University Provider Number: 00025B
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The following message was posted to: PharmPK
There is a web page: www.drugdel.com that can help you in getting an
controlled delivery systems and novel approaches for drug delivery, but
me stress that it is an industry based website that highlights and to
point advertises the advantages of the pharmaceutical systems that the
industry has developed and sometimes commercialised.
In controlled drug release the success story is OROS by Alza (now part
J&J) which is an osmotic tablet with a laser drilled hole. In terms of
hydrophillic matrices examples such as TIMREx (Penwest) or Contramid
(Labopharm) are helpful.
In new drug delivery systems you could classify them by the route they
administered. In this web you will find examples of buccal/mucosal,
pulmonary and polymeric delivery systems.
In the excipient list you will find information about solubilising
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