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Can any one let me know the pKa values of the Rifapentine.
Rifapentine being the derivative of the Rifampicin, only change is
of N-CH3...its is N-Pentene ring.
Does this change in the Nitrogen attached group, change a lot the pKa
value of the drug?
The pKa value of the Rifampicin is 1.7 (due to three OH group of
napthelene ring) and 7.9 (due to N-CH3)
Kindly let us know, if any text references of the Rifapentine pKa
Have a nice day!
Mr. Bhusari Sachin, Res: C/O Kole P L
M. Pharm research Scholar, 75/4, Pooja Marg
Pharmacy Group, Vidya Vihar,
Birla Institute of Technology and Science, BITS, Pilani
Pilani, Rajasthan 333031
Alt Email: sachu_om.-at-.yahoo.com, sachu_bits.aaa.rediffmail.com
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