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The following message was posted to: PharmPK
I need some informations concerning the hepatocellularity (hepatocyte
number/ g liver), the total P450 content (nmol/ g liver), the microsomal
protein yield (mg prot/ g liver) and the liver blood flow (ml/min/g
liver)
in the beagle dog and the cynomolgus monkey together with the literature
that refers to these parameters. Thanks in advance for your help,
M.N. SOLBES
Study Director of Drug Metabolism
DMPK Department
Merck Santé France
115, av Lacassagne
F 69424 Lyon cedex 03
France
e-mail : marie-noelle.solbes.aaa.merck.fr
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