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Hi,
Anybody has any info on how tramadol hydrochloride is
metabolised?
So far, there are lots of materials on the involvement
of cytochrome P450 IID6 (CYP2D6) in its metabolism.
Recently however, CYP3A4 has also been discovered to
be involved. Nevertheless, the percentage contribution
of each pathway was not mentioned.
Any kind of information regarding the metabolism of
tramadol is greatly appreciated.
Thanking in advance,
Ms. Gan Siew Hua,
PhD candidate,
Jabatan Farmakologi,
Pusat Pengajian Sains Perubatan,
Universiti Sains Malaysia,
16150 Kubang Kerian,
Kelantan, MALAYSIA.
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)