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The following message was posted to: PharmPK
Hello:
Can anyone provide me with values for the % of brain volume occupied by
blood? I once researched this question and came up with a value of about
3% but I have since lost the references. Thanks for your help.
Richard Knapp
Aventis Pharmaceuticals
Bridgewater, NJ 08807
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[A few more replies - db]
From: "Gregorio Encina"Date: Thu, 14 Mar 2002
16:08:24 +0100
To: david.aaa.boomer.org
Subject: Re: PharmPK Volume of Blood in Brain
The following message was posted to: PharmPK
Hello Richard
Perhaps in this article you have the answer
Physiological parameters in Laboratory Animals and Humans Brian Davies
and Tim Morris
Pharmeutical Research, vol 10, Nž 7 1093-1095 (1993)
Gregorio Encina
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From: tongw.aaa.mskcc.org
Date: Thu, 14 Mar 2002 10:19:51 -0500
To: david.at.boomer.org
Subject: Re: PharmPK Volume of Blood in Brain
The following message was posted to: PharmPK
Richard,
Residual blood volume in brain are 30 ul/g for cat and 11 ul/g
for dog, from "Blood and other body fluids", p. 9, ed. DS
Dittmer, Federation of American Soc. for Exp. Biology, 1961.
Bill Tong
Memorial Sloan Kettering
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From: "Melethil, Srikumaran K."Date: Thu, 14 Mar
2002 12:26:15 -0600
To: david.at.boomer.org
Subject: RE: PharmPK Volume of Blood in Brain
The following message was posted to: PharmPK
Information on this issue can be found in the paper by Tang and
Melethil, Pharm. Res. 12, 1085, 1995.
Srikumaran K. Melethil, Ph.D., JD (2002) Professor, Pharmaceutics and
Medicine
University of Missouri- Kansas City
203B Katz Hall (School of Pharmacy)
Kansas City, MO 64110
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