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Can we expect some changes in the physiology of human Blood Brain
Barrier in case of Brain tumors (Astrosarcoma) and resultant alteration
in drug levels in the CSF as compared to healthy human beings.
I requestsome guidance regarding practical conduct of pharmacokinetic
profiling of an anticancer drug in CSF of human subjects
Thanks in advance,
Vijay Vishesh Upreti.
Drug Metabolism and Pharmacokinetics
Discovery Research, Dr. Reddy's Laboratories Ltd. (DRL)
Miyapur. Hyderabad-500 050. INDIA
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