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The following message was posted to: PharmPK
We have used up to 2% SDS when testing the dissolution rate of some
steroids, so you may just want to test higher levels. I have also seen
groups use at least 2 different IPA levels added to PBS and then
interpolation of dissolution in PBS, although this may be problematic.
Jim
James D. Talton, Ph.D.
President & CEO
Nanotherapeutics, Inc.
12085 Research Drive, Suite N
Alachua, FL 32615
(386) 462-9663
(386) 462-2087 fax
www.nanotherapeutics.com
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)