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The following message was posted to: PharmPK
Dear Colleagues,
I would be grateful for a source of information on a Glucosamine HCl
HPLC assay, if it already exists somewhere.
Thank you.
Sincerely,
Louisa
Dr Louisa Alfazema
Tel: 01329 832511
Fax: 01329 834262
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The following message was posted to: PharmPK
Hi,
Hope this is helpful...
Liang Z, Leslie J, Adebowale A, Ashraf M, Eddington N.
Determination of the nutraceutical, glucosamine hydrochloride,
in raw materials, dosage forms and plasma
using pre-column derivatization with ultraviolet HPLC.
J Pharmaceut Biomed Anal 1999; 20: 807-814.
The above paper is cited in:
Adebowale A, Du J, Liang Z, Leslie JL, Eddington ND.
The bioavailability and pharmacokinetics of glucosamine hydrochloride
and low molecular weight chondroitin sulfate after single and multiple
doses to beagle dogs.
Biopharm Drug Dispos. 2002 Sep;23(6):217-25.
Sangeeta
Sangeeta Raje, Ph.D
Clinical Pharmacokineticist
Clinical Pharmacology
Wyeth Research and Pharmaceuticals
Collegeville, PA 19426
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