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Does anyone know the effect of hepatic impairment on bile secretion in
to
the gut ?
Rajeev
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The following message was posted to: PharmPK
It depends on the type of impairment. From my clinical experience, the
bile
secretion into the gut is generally decreasing in terms of the amount
and
content of the secretion.
Jie
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The following message was posted to: PharmPK
Do you have any quantitative data? How much decrease on e.g. severe
hepatic
impairment?
How bile composition affecten?
Kind regards,
Adrienne
AJAM Sips, PhD
National Institute of Public Health & the Environment
Center for Substances and Integrated Risk Assessment, U339
P.O. Box 1
3720 Bilthoven
The Netherlands
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