PharmPK Discussion - Cardiac output, physiological values

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On 10 Oct 2004 at 08:35:12, Ananda Sen (senuic.-a-.yahoo.com) sent the message


Hi,
Can someone please tell me the cardiac output in
healthy male rats.
Also, is there a documentation for human and animal
physiological parameters like BP, HR, organ blood flow
rates?
Thanks
Ananda

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On 11 Oct 2004 at 09:06:05, Renee Ying Hong (yinghong.-at-.pharm.usyd.edu.au) sent the message


Hello, Ananda
Please refer to this paper:Pharm Res. 1993 Jul;10(7):1093-5. Davies B,
Morris T. Physiological parameters in laboratory animals and humans.
Kind Regards, Renee

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On 10 Oct 2004 at 22:58:19, jbyczkowski.-a-.netscape.net sent the message


Ananda Sen  wrote:
"...Can someone please tell me the cardiac output in
healthy male rats. ..">>
Please see:
ILSI. 1994. Physiological Parameter Values for PBPK Models (R. Brown,
Ed.). A Report Prepared by the International Life Science Institute,
Risk Science Institute for US EPA in 1994, Washington, DC.
and a peer-reviewed version of the original report:
Brown .R.P, DelpM.D., Lindstedt, S.L., Rhomberg, L.R., Beliles,R.P.
1997.
Physiological Parameters Values for Physiologically Based
Pharmacokinetic
Models, Tox. And Ind Healt. Vol 13 (4) p. 407-484.
See also response by Spiresgate.at.aol.com, on 29 Sep 2001, at PharmPK
Discussion List Archive:

Best wishes.
          Janusz Z. Byczkowski, Ph.D.,D.Sc.,D.A.B.T.
                          Consultant
                      212 N. Central Ave.
                      Fairborn, OH 45324
                      voice (937)878-5531
                    e-mail januszb.-at-.AOL.com
     homepage: http://members.aol.com/JanuszB/index.html
JZB Consulting web site: http://members.aol.com/JanuszB/consult.htm

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