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My aim of work is to simulate the drug metabolism in hepatocytes.
Therefor I need hepatic drug concentrations. Unfortunately, I've got
only blood concentrations of the drugs of my interest. So in a first
simulation I assumed concentration equality. To get nearer to the real
situation, which rough concentration factor shall i assume? (which fits
in most cases, 10, 50, 100, ...)?
Joachim Bucher, Dipl.-Ing.
Institut fu"r Bioverfahrenstechnik
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