PharmPK Discussion - Enterohepatic circulation after IV and IM

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On 23 Mar 2004 at 09:06:23, "Khalid Alkharfy" (alkharfy.aaa.ksu.edu.sa) sent the message

Dear All,
Is it possible to observe an enterohepatic circulation with IV but not
with IM administration of a same drug? And could this explain some
difference in the terminal half-life of the drug following IV and IM
injection? Any references will be appreciated.
Regards,
Khalid Alkharfy, Pharm.D., Ph.D.
Assistant Professor of Clinical Pharmaceutical Sciences
Department of Clinical Pharmacy
School of Pharmacy, KSU
PO Box 2457
Riyadh 11451
Saudi Arabia
VOICE: 01-467-7494
FAX: 01-467-7468

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