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Dear all,
Can any body provide me Pharmacokinetics and Pharmacodynamics on
Fampridine-SR (4-aminopyridine).
Thanks,
sriraj
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See:
Hayes KC, et al, "Pharmacokinetics and safety of multiple oral doses of
sustained-release 4-aminopyridine (Fampridine-SR) in subjects with
chronic,
incomplete spinal cord injury," **Arch Phys Med Rehabil** 2004
Jan;85(1):29-34:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=pubmed&dopt=Ab
stract&list_uids=14970964
Hayes KC, et al, "Pharmacokinetic studies of single and multiple oral
doses
of fampridine-SR (sustained-release 4-aminopyridine) in patients with
chronic spinal cord injury," **Clin Neuropharmacol** 2003
Jul-Aug;26(4):185-92:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=pubmed&dopt=Ab
stract&list_uids=12897638
Hayes KC, et al "Pharmacokinetics of an immediate-release oral
formulation
of Fampridine (4-aminopyridine) in normal subjects and patients with
spinal
cord injury," **Clin Pharmacol** 2003 Apr;43(4):379-85:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=pubmed&dopt=Ab
stract&list_uids=12723458
Best Regards,
Jim Schmidt
Lexicon Genetics
DMPK - Rm C222b
8800 Technology Forest Place
The Woodlands, TX 77381
jschmidt.-a-.lexgen.com
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)