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I'm using PEG 400 as a vehicle (the drug is very insoluble in many
compounds). The vehicle is PEG 400 90% and DMSO 10 % (a stock solution
of the drug). I'd like to know if these vehicle (almost entirely PEG
400) is absorbed by subcutaneous route (250 uL, mice). I'd like to
reach maximum plasma levels 45 minutes to 1 hour after dosing mice.
Thanks for any help !
Rodrigo Guabiraba Brito
Biological Sciences Graduating Student
Laborat\0xDBrio de Imunofarmacologia
Bloco O4 Sala 202 / Departamento de Bioqu\0xCCmica e Imunologia
Instituto de Ci\0xCDncias Biol\0xDBgicas / Universidade Federal de Minas Gerais
Av. Ant\0xD9nio Carlos, 6627 - Pampulha - CEP 31270-901
Belo Horizonte - Minas Gerais - Brasil
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