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Gozzi et al., (JPET, 291, 199-203, 1999) had proposed an indirect PD
model, including an intracellular compt. to study the supression of LPS
induced TNF-alpha in an in vivo model. I am wondering if any one had
utilized this model. If so, could you please let me know the detailsof
model-fitting, including WinNonlin code.
Thanks,
- Sekhar
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