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if any one can tell the site of absorption of norfloxacin. it would be
great help to me. little or no assumption plz.
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Like other fluoroquinolones, Norfloxacin is absorpbed from upper small
intestine. Specific process or mechanism of absorption is not known.
Many studies have been done for studying the absorption of
fluoroquinolones. Solubility of fluoroquinolones reduces at pH values
near isoelectric points. So GI pH definitely affects the
bioavailability of the Norfloxacin. It is postulated that it is
absorbed by a facilitated process.
Hope this helps
Kole Prashant, M.Pharm (Ph.D)
Birla Institute of Technology and Science, Pilani
Phone: (O) 01596-245074-Ext-458
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