Dear All,Back to the Top
Generally we have to use plasma or serum to verify the drug
concentration in pharmacokinetics studies or drug monitoring. In this
way, total drug is measured and sometimes protein precipitation or
liquid-liquid extraction are used. Are these methods of extraction able
to separate drugs from protein binding? What are the evidences of it?
Which sample is more appropriate to TDM: serum or plasma?
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (firstname.lastname@example.org)