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I am looking for some information or method to determine topiramate
using a
conventional HPLC.
I heard that there may be a method to determine topiramate using HPLC.
If not possible, is there any other method to determine it (i.e.
derivatization.. ) except LC-MS or GC.
I need urgent help.
Thanks
Ji-Young Park
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Ji-Young Park,
Here is one reference that might help.
Pediatr Neurol. 2003 Aug;29(2):143-7.
Topiramate concentration in saliva: an alternative to serum monitoring.
Miles MV, Tang PH, Glauser TA, Ryan MA, Grim SA, Strawsburg RH, deGrauw
TJ, Baumann RJ.
Pathology and Laboratory Medicine, Cincinnati Children's Hospital
Medical Center, Cincinnati, Ohio 45229, USA.
Manoj
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