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Dear All,
I need help from you in understanding about first pass metabolism and
how a drug is available systemically after absorption and after first
pass metabolism.
If you have any articles regarding the above please send me which will
be very useful for me in understanding the concepts.
With Regards,
V.Radhakrishna
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Please find some papers from Drug Metabolism and Disposition Journal:
http://intl-dmd.aspetjournals.org/cgi/search?
pubdate_year=&volume=&firstpage=&author1=&author2=&title=&andorexacttitl
e=and&titleabstract=&andorexacttitleabs=and&fulltext=first+pass+hepatic+
metabolism&andorexactfulltext=and&fmonth=Jan&fyear=1973&tmonth=Sep&tyear
04&fdatedef=1+January+1973&tdatedef=8+September+2004&hits=10&sortspec
=relevance&sendit=Search
Vlase Laurian
Dept. of Pharmaceutical Technology and Biopharmaceutics
Faculty of Pharmacy
University of Medicine and Pharmacy "Iuliu Hatieganu"
13, Emil Isac
Cluj-Napoca, Cluj 3400, Romania
vlaselaur.aaa.yahoo.com
online on Yahoo Messenger
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)