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The following message was posted to: PharmPK
I wondered if anybody could offer some advice concerning the analysis
of clonidine in human plasma for pharmacokinetic studies?
We have done some preliminary work using HPLC with UV detection but
are finding it difficult to achieve the required assay sensitivity.
Hence, we are investigating other options. Does anybody know of a
commercially available kit for quantifying clonidine by
radioimmunoassay? I would be grateful for any information on this or
any opinions on alternative analysis methods for clonidine (such as
With thanks and best wishes
Dr. Ann Rigby-Jones
Research Fellow, Anaesthesia Research Group, Peninsula Medical
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