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Does anyone have information or literature references that address
the bioanalytical method for rosiglitazone maleate for development/
validations and sample analysis for it and metabolites in serum/
plasma ?.
Any references will be very helpful
Thanks to all.
Piedad
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The following message was posted to: PharmPK
Dear Piedad
You can find many articles related to your subject in
www.pubmed.com.
below some titles related to pioglitazone analysis in human plasma
hope they help.
1. Simplified method for determination of rosiglitazone in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr 25;803(2):
317-20.
2. Simultaneous determination of glipizide and rosiglitazone unbound
drug
concentrations in plasma by equilibrium dialysis and liquid
chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Mar 5;801(2):265-72
3. Simple method for the determination of rosiglitazone in human plasma
using a commercially available internal standard.
Biomed Chromatogr. 2003 Sep;17(6):417-20.
4. Liquid chromatographic method for the determination of
rosiglitazone in
human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 5;788(1):37-44
Isra' Admour, M.Sc Pharm
Regualtory Affairs Director
International Pharmaceutical Research Center (IPRC)
Tel: +962-6-5627651/52/48 (ext. 225)
PO Box 963166, Amman11196, Jordan
www.iprc.com.jo
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The following message was posted to: PharmPK
Dear Piedad
You may find these references useful.
Kim KA, Park JY.Simple and extractionless high-performance
liquid chromatographic determination of rosiglitazone in human plasma
and application to pharmacokinetics in humans. Biomed Chromatogr.
2004 Oct;18(8):613-5.
Lin ZJ, Desai-Krieger D, Shum L. Simultaneous determination of
glipizide and rosiglitazone unbound drug concentrations in plasma by
equilibrium dialysis and liquid chromatography-tandem mass
spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Mar
5;801(2):265-72
Mamidi RN, Benjamin B, Ramesh M, Srinivas NR. Simple method for
the determination of rosiglitazone in human plasma using a
commercially available internal standard. Biomed Chromatogr. 2003 Sep;
17(6):417-20.
Mamidi RN, Chaluvadi MR, Benjamin B, Ramesh M, Katneni K, Babu
AP, Bhanduri J, Rao NM, Rajagopalan R. HPLC method for the
determination of rosiglitazone in human plasma and its application in
a clinical pharmacokinetic study. Arzneimittelforschung. 2002;52(7):
560-4.
Muxlow AM, Fowles S, Russell P. Automated high-performance
liquid chromatography method for the determination of rosiglitazone
in human plasma. J Chromatogr B Biomed Sci Appl. 2001 Mar 5;752(1):
77-84.
Best wishes
Ann
Dr. Ann Rigby-Jones
Research Fellow, Anaesthesia Research Group, Peninsula Medical
School, Universities of Exeter & Plymouth, UK
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