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Dear All:
I would like to know how much DMSO can be used in PAMPA: I've seen 1%
everywhere, also I have a pair of papers in which it is used at 5%
and it has been reported upto 30% (seen in "Absorption and Drug
Development...", by A.Avdeef).
Specifically I want to know if DMSO can be used at 8% in PAMPA. I
would thank any refference or information about it.
Best regards,
Ixchel De La Luz.
Q.F.B. Ixchel De La Luz Martinez
Laboratorio de Biofarmacia y Tecnologia Farmaceutica
Facultad de Farmacia UAEM
Av. Universidad 1001, Col. Chamilpa
Cuernavaca, Morelos 62120, MEXICO
+52(777)3297089 ext 7134 & 7135
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Dear
Following article might help you in identifying % of DMSO in PAMPA.
Combined application of parallel artificial membrane permeability
assay and Caco-2 permeability assays in drug discovery
Journal of Pharmaceutical Sciences
Volume 93, Issue 6, Date: June 2004, Pages: 1440-1453
Edward H. Kerns, Li Di, Susan Petusky, Michele Farris, Rob Ley, Phil
Jupp
Jignesh Kotecha
Scientist 1
Torrent Pharma. Ltd.
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (david@boomer.org)