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Dear All,
I am trying to familiarize with the use of fractal kinetics in
pharmacokinetic modeling, could anbody provide me references or names
of textbook that I could refer for basic understanding of the subject.
Thank you in advance
Varun Goel
[Is that anything like stochastic modeling ;-) - db]
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The following message was posted to: PharmPK
Hi Varun,
I have pasted some refs on fractal PK that I found useful. The first
one
from the physics group is quite interesting. The Panos Macheras refs as
well provide more background information.
Best Regards,
Rob Bies
University of Pittsburgh
Authors
Fuite J. Marsh R. Tuszynski J.
Title
Fractal pharmacokinetics of the drug mibefradil in the liver.
Source
Physical Review E. Statistical, Nonlinear, & Soft Matter Physics. 66(2
Pt
1):021904, 2002 Aug.
Authors
Karalis V. Macheras P.
Title
Drug disposition viewed in terms of the fractal volume of distribution.
Source
Pharmaceutical Research. 19(5):696-703, 2002 May.
Authors
Macheras P.
Title
A fractal approach to heterogeneous drug distribution: calcium
pharmacokinetics.
Source
Pharmaceutical Research. 13(5):663-70, 1996 May.
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