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The saturable (Km and Vmax) and non-saturable kinetics of large
neutral amino acids at the blood-brain barrier is well known. But
I've been unable to find equivalent values for the drug levodopa,
which shares the same transporter (LAT1) - does anyone know where I
can find these values?
Kim Z Travis
Syngenta, UK
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)