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The following message was posted to: PharmPK
Dear All,
I was wondering if someone can help me find a reference or
maybe give me an experimental number on the rate of
paclitaxel internalization into cells (specifically smooth
muscle cells) as well as the rate constant of
association/dissociation of paclitaxel with /from tubulin and
albumin. If these values are not readily obtainable, these
rates for a homologous compound (any of the taxanes) will do
for now.
Many thanks in advance,
Murad
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)