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I am searching information about paracetamol pharmacokinetics (AUC,
t1/2, Cmax, F) in pigs but there is nothing published.
Do you know something about this?
Jordi Lopez
SPCEN INVEST XXI, AEIE
c/ Cervantes, 29-31
43206 Reus (TARRAGONA)
Tel/Fax: 977-328094
e-mail: spcen-aeie.at.terra.es
http://www.spcen.com
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EMEA/MRL/551/99-FINAL. PARACETAMOL SUMMARY REPORT. February 1999
Monshouwer M., Witkamp R.F., Pijpers A., Verheijden J.H., van Miert
A.S. Dose-dependent pharmacokinetic interaction between antipyrine
and paracetamol in vivo and in vitro when administered as a cocktail
in pig. Xenobiotica 1994; 24: 4, 347-55
Monshouwer M., Witkamp R.F., Nijmeijer S.M., Pijpers A., Verheijden
J.H., Van Miert A.S. Selective effects of a bacterial infection
(Actinobacillus pleuropneumoniae) on the hepatic clearances of
caffeine, antipyrine, paracetamol, and indocyanine green in the pig.
Xenobiotica 1995; 25: 5, 491-9
Gazzard BG, Ford-Hutchinson AW, Smith MJ, Williams R. The binding of
paracetamol to plasma proteins of man and pig. J Pharm Pharmacol 197;
25:12, 964-7
Paola Anfossi
Dipartimento di Sanita Pubblica Veterinaria e Patologia Animale
Servizio di Prova di Farmacologia e Tossicologia
Via Tolara di Sopra 50
40064 Ozzano Emilia (BO)
tel. fax +39.051.2097513
e-mail:paola.anfossi.at.unibo.it
sito web: http://www.dspvpa.unibo.it/DSPVPA/default.htm
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)