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Dear sir,
I have a query about the dissolution media for a fixed dose
combination product (FDC)of Rabeprazole- Domperidone SR Tablets. where
the
solubilty of the individual drugs are different.In this case and also
in similar cases how the dissolution media should be selected? what
should be the criteria for the selection of the media?
Suppose the individual drug solubility is pH dependent (One soluble in
acid and another in Basic), how the media should be selected for
dissolution?
Prof. (Dr.) T.K. PalDepartment of Pharm. Technology,
Jadavpur University,
CALCUTTA -- 700 032, INDIA.
Telefax: 91-033-2414 6967 (O)
Fax : 091-033-2414 6967
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