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Hello,
have a look at this paper
Bioorganic & Medicinal Chemistry 12 (2004) 6107-6118
Ionization, lipophilicity, and molecular modeling
to investigate permeability and other biological
properties of amlodipine
Giulia Caron,* Giuseppe Ermondi, Alessandro Damiano, Laura Novaroli,
Oksana Tsinman, Jeffrey A. Ruell and Alex Avdeef,
Best regards
Giulia Caron
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