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Dear all,
I would like to know that is there any reference available to list
biopharmaceutic classification system (BCS) drugs?.
Since i am working on BCS II drug, if i know the list of drugs in
this category that will be useful for me.
Regards,
Francis
Manipal
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The following message was posted to: PharmPK
Hi Francis,
Hope these recent reviews help.
1. Wu CY, Benet LZ. Predicting drug disposition via application of BCS:
transport/absorption/ elimination interplay and development of a
biopharmaceutics drug
disposition classification system. Pharm Res. 2005, 22(1):11-23.
2. Varma MV, Khandavilli S, Ashokraj Y, Jain A, Dhanikula A, Sood A,
Thomas NS, Pillai O,
Sharma P, Gandhi R, Agrawal S, Nair V, Panchagnula R. Biopharmaceutic
classification
system: a scientific framework for pharmacokinetic optimization in
drug research. Curr
Drug Metab. 2004, 5(5):375-88.
3. Lennernas H, Abrahamsson B. The use of biopharmaceutic
classification of drugs in drug
discovery and development: current status and future extension. J
Pharm Pharmacol. 2005,
57(3):273-85.
Good luck,
Sripal
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Dear Francis,
These two papers are based on WHO drug list.
1: Kasim NA, Whitehouse M, Ramachandran C, Bermejo M, Lennernas
H, Hussain AS, Junginger HE, Stavchansky SA, Midha KK, Shah VP,
Amidon GL.
Molecular properties of WHO essential drugs and provisional
biopharmaceutical classification.
Mol Pharm. 2004 Jan 12;1(1):85-96.
PMID: 15832504 [PubMed - indexed for MEDLINE]
2: Lindenberg M, Kopp S, Dressman JB.
Classification of orally administered drugs on the World Health
Organization Model list of Essential Medicines according to the
biopharmaceutics classification system.
Eur J Pharm Biopharm. 2004 Sep;58(2):265-78. Review.
PMID: 15296954 [PubMed - indexed for MEDLINE]
Regards,
Ma Guangli
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The following message was posted to: PharmPK
Dear Francis,
Find some useful link which will help you in BCS'
http://www.fda.gov/cder/guidance/3618fnl.htm
http://www.fda.gov/cder/OPS/BCS_guidance.htm
http://www.dissolutiontech.com/DTresour/0502art/DTMay02_art1.htm
http://acronyms.thefreedictionary.com/Biopharmaceutics+Classification
+System
http://www.absorption.com/assets/adeptiv/upload/attach/Copy%203%20of%
Sanjeev
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The following message was posted to: PharmPK
Please look for the desired information using the following hyperlink:
http://www.tsrlinc.com/search3.cfm
ZTS
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Francis,
The compounds which go in BCS class II as per my knowledge are like
glebenclamide, piroxicam, nifedipine and many NSAIDs.
Regards,
Dr Antaryami Maharana
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Dear Francis,
have a look to this publication which is very helpful in
understanding the
BCS classification system and its restrictions (more specifically on
class
II) :
Modern bioavailability, bioequivalence and biopharmaceutics
classification
system. New scientific approaches to international regulatory standards
Raimar Loebenberga and Gordon L. Amidon,
European Journal of Pharmaceutics and Biopharmaceutics
Volume 50, Issue 1 , 3 July 2000, Pages 3-12
Kind regards
Stephane
--
Beilles Stephane, Ph.D
Preformulation Study Manager
Fournier Pharma
42, Rue de Longvic
F-21300 CHENOVE
tel : +33 (0) 3 80 44 32 52
Fax : +33 (0) 3 80 44 32 70
s.beilles.-at-.fr.fournierpharma.com
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