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I am not sure if my response is still "timely" - i have just found
your message this morning.
Have you thought of 'microdosing'? with AMS sensitivity, you need
only 20mcl of plasma samples and less than 100nci. dose to get full
kinetics. The dose is so small that it is consider "subtoxic".
While I was at UCD, I had received approval for a study of
bioconversion of b-car on infants applying microdosing/AMS. The oral
dose was about 20nci c14b-car.
Le Thuy Vuong, MBA, PhD
Vitalea Science, Inc.
1233 East Beamer Street, Unit C
Woodland, CA 95776
[Original from Oct 2004 - db]
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