PharmPK Discussion - Do anticancer drugs affect Caco-2 cell lines

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On 19 Aug 2006 at 03:43:29, Nisha K R (nishavenkatesh.-a-.yahoo.co.in) sent the message


Dear forum,
Will Caco-2 cell line be adversely affected by anticancer drugs? If
no, why not?
Regards
Nisha K R

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On 20 Aug 2006 at 19:23:21, "d.s samiulla" (dssamiulla.-at-.yahoo.com) sent the message


Dear Nisha,

Well, the anticancer drugs will affect caco-2. But the time and conc
req to produce apoptosis is different from Permeability assay ( which
is for maximum of 2h).

regards,
Samiulla
Aurigene

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