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I need to use tween 80 to disperse microspheres coated with
BS-1 lectins. These spheres are then infused into the Rat. It is
important to use Tween 80 because the beads tend to aggregate and
form clumps in the vessel which could be a potential problem. My
question to you is, will tween 80 cause any interference when infused
in vivo? I would really apprciate if you can explain in terms of
interference with the proteins on the bead surface, endothelial cells
or even more specifically glycocalyx structure?
Thanks so much.
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