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The following message was posted to: PharmPK
Hi,
Can someone please tell me the dose needed for a 90 day repeat dose
tox/TK study in rats? Does it need to be the NOAEL dose?
Thanks
Ananda
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dear
before go for the actual study 90days initially dose range finding
study do be done for 14 days . Then you need to fix the dose for 90
days .normally dose range will be 0- 500mg/kg/day.
i hope this helps for u.thanks.
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