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I would like to receive information about gatifloxacin and
ethilcarbamate (urethane), if there is some interaction between
them. I use this substance for anesthesia, but rats don't survive
more than 2-3 hours after gatifloxacin administration. I have tried
pentobarbital and xilazine and cetamine, diferent associations, but
no positive results were obtained.
Somebody knows some interaction between gatifloxacin and urethane?
Which are the alternatives possible?
I solubilize gatifloxacin with HCl 0.1N and add NaCl solution 0.9%.
The pH of solution for administration is between 4-5. Is there some
problem about it?
Leandro Tasso _ UFRGS BRAZIL
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