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The following message was posted to: PharmPK
Dear all,
I know that a significant difference between real
concentration and predicted concentration of a drug
may reflect bad selection of pharmacokinetic
parameters of the model used by software pk program
for prediction.
I have got this result in some data related to lithium
concentration using two compartment model.
What are the suggestions to improve the model?!
Ehab
Assiut university, Egypt
[How much data do you have, have you tried other models, what shape
is the residual plot? See http://www.boomer.org/c/p3/c19/c1901.html -
db]
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