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Dear Colleagues,
I am interested in scaling up the nonlinear pharmacokinetics data
from animals to human. Could anyone kindly help me by sending
references?
With best regards.
-
Hong Lu
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Dear Hong Lu,
Hi, I am also working on interspecies allometric scaling
problems. :)
Maybe these could help you:
The Prediction of Human Pharmacokinetic Parameters from Preclinical
and In Vitro Metabolism Data
http://jpet.aspetjournals.org/cgi/content/full/283/1/46
Mahmood,I.(2005) Interspecies Pharmacokinetic Scaling: Principles and
Application of Allometric Scaling. Pine House Publishers, Rockville,MD.
Good luck
Ma Guangli
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