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Hello .. I am testing urine levels of drugs of abuse and am looking
for quantitative methods to estimate whether the rate of
disappearance of TLC of cocaine over time is consistent with the
known pk of these substances. Are formulae or nomograms available?
A specific example would be a 200 lb male age 50 tests at 1700 ng/ml
benzoylecogonine in urine September 20. Retested September 29 the
level is 450 ng/ml. Can I conclude that this man was not re-dosed
with cocaine after the first test? This would be useful if it is
consistent with the known pharmacokinetics.
THANK YOU IN ADVANCE
PETER FRANKLIN MD
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