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Dear colleagues,
We are pleased to announce the release of PK-Sim(R) Version 3.0. PK-
Sim(R) is the most sophisticated software for PBPK simulations in
pharmaceutical R&D, provided by Bayer Technology Services. Being
based on a generic whole body PBPK model it provides a convenient
user-interface and implemented functions supporting the
parameterization of the model according to compound properties. Thus
it is easily applicable in all phases of R&D and allows accomplishing
simulations for new substances in minutes.
The most important new features of Version 3 are:
.. Clearance Scaling for Children based on the known adult
clearance value
.. Calculation of dissolution kinetics of a solid particle
formulation from particle size distribution and pH-dependent solubility
.. Flexible administration of dose by arbitrary functions of
uptake into any (sub-)compartment of the model
.. Output of metabolized fraction for each metabolic process
described in the simulation
.. Read-Only Mode allowing for full access to all previously
generated projects (without possibility to run new simulations) even
if no license is available - Allows e.g. sharing of information with
colleagues having no access to a full license.
New Package: "PK-Sim Absorption"
Additionally the range of available packages of different
functionality has been extended by the new "Absorption Package",
which provides stand alone simulation of the gastro-intestinal
transit and absorption process and serves particularly the needs of
scientists involved in biopharmaceutics and formulation development.
To find more information please visit our website http://www.pk-
sim.com or send an inquiry for information to sales.aaa.pk-sim.com
Best Regards
Walter Schmitt
--
Bayer Technology Services GmbH
PT-AS-SB
Monheim, 6550
Tel.: +49 2173 38 4546
Fax: +49 2173 38 9694546
E-Mail: walter.schmitt.-at-.bayertechnology.com
Internet : http://www.bayertechnology.com
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)