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The following message was posted to: PharmPK
Dear Colleagues,
Is there any reliable
data or published literature on urinary 6beta-OH-cortisol/cortisol
ratio for
healthy men between 18-50 yr (normal range or mean +/- SD)?
Rostam
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The following message was posted to: PharmPK
Dear colleague,
Sorry for this delayed reply!.
Please review the following two papers for urinary
6beta-OH-cortisol/cortisol ratio in adults:
1- ElDesoky Ehab S, et al. Study of urinary
6beta-OH-cortisol/cortisol ratio in spot urine sample
as a biomarker of 3A4 enzyme activity in healthy and
epileptic subjects of Egyptian population.
Pharmacological Research 2005; 51: 575-580.
2- ElDesoky Ehab S, et al.Study of the urinary ratio
of urinary 6beta-OH-cortisol/cortisol as a biomarker
of cyp 3A4 activity in Egyptian patients with chronic
liver diseases. Drug Target Insights 2006; 2: 157-164.
regards,
Professor Ehab S ELDesoky
Professor of Pharmacology
Assiut University
Assiut, Egypt.
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